Drs Alan Woolf, Mara Seeley, and Alicia Frasier will explore the history, environmental persistence, health impacts and clinical diagnosis and management of exposure to polychlorinated biphenyls (PCBs) and related chemical compounds. The presentation will highlight how PCBs have contaminated ecosystems globally and outline their long-term health effects, including cancer risk, endocrine disruption, and developmental problems. Groups that are particularly vulnerable to PCB toxicity will be described, as well as some clinical and public health strategies to prevent their exposure to these chemicals. CME and CEU’s are available.